Description

Generate GWAS association studies

Input

name:type
description
pattern

meta

:map

Groovy Map containing genotype sample information for PLINK BED/BIM/FAM input e.g. [ id:‘test’ ]

bed

:file

PLINK binary biallelic genotype table file

*.{bed}

bim

:file

PLINK extended MAP file

*.{bim}

fam

:file

PLINK sample information file

*.{fam}

meta2

:map

Groovy Map containing genotype sample information for VCF input e.g. [ id:‘test’ ]

vcf

:file

Variant calling file (vcf), optionally gzip-compressed

*.{vcf,vcf.gz}

meta3

:map

Groovy Map containing genotype sample information for BCF input e.g. [ id:‘test’ ]

bcf

:file

PLINK variant information + sample ID + genotype call binary file

*.{bcf,bcf.gz}

meta4

:map

Groovy Map containing phenotype information for --pheno e.g. [ id:‘test’ ] The phenotype file can be paired with BED/BIM/FAM, VCF, or BCF genotype inputs

phe

:file

PLINK phenotype file passed with --pheno for BED/BIM/FAM, VCF, or BCF input modes. Phenotypes can be read from the third column by default or from a named column with --pheno-name via module arguments

*.{phe}

Output

name:type
description
pattern

assoc

meta

:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

*.{assoc,qassoc}

:file

PLINK GWAS association output file (.assoc for case/control traits, .qassoc for quantitative traits)

*.{assoc,qassoc}

log

meta

:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

*.log

:file

PLINK GWAS association log file

*.{log}

nosex

meta

:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

*.nosex

:file

PLINK GWAS association file that retains phenotypes for samples with ambiguous sex. Produced with the option —allow-no-sex

*.{nosex}

${task.process}

:string

The name of the process

The name of the tool

The expression to obtain the version of the tool

Topics

name:type
description
pattern

versions

${task.process}

:string

The name of the process

The name of the tool

The expression to obtain the version of the tool

Tools

plink
GPL

Whole genome association analysis toolset, designed to perform a range of basic, large-scale analyses in a computationally efficient manner.